Guaifenesin (Guaiphenesin/Gyceral Guaiacolate)

Indications
 Oral
Cough
Adult: 200-400 mg every 4 hr. Max: 2.4 g/day.
Child: 6-12 yr: 100-200 mg; 2-6 yr: 50-100 mg; 6 mth-2 yr: 25-50 mg. To be given every 4 hr. Max: 6-12 yr: 1.2 g/day; 2-5 yr: 600 mg/day.
Contraindications
 Hypersensitivity.
Warnings / Precautions
 Persistent cough e.g. occurs with smoking, asthma, chronic bronchitis, or emphysema; cough accompanied by excessive secretions; cough with a fever, rash, or persistent headache; Pregnancy, lactation. Porphyria.
Adverse Reactions
 GI discomfort, nausea and vomiting; dizziness, drowsiness, headache; rash; decreased uric acid levels; urinary calculi (large doses).
Lab Interactions
 Possible color interference with determination of 5-HIAA and VMA; discontinue for 49 hrs prior to test.
Mechanism of Actions
 Guaifenesin increases the volume and reduce the viscosity of tenacious sputum and is used as an expectorant for productive cough.
Absorption: Well absorbed in the GI tract.
Excretion: Urine.
ATC Classification
 R05CA03 - guaifenesin ; Belongs to the class of expectorants. Used in the treatment of wet cough.
Available As
  • Guaiphenesin 1 mg
  • Guaiphenesin IP 1.25 mg
  • Guaiphenesin IP 10 mg
  • Guaiphenesin 10 mg
  • Guaiphenesin 100 mg
  • Guaiphenesin Hcl 100 mg
  • Guaiphenesin IP 100 mg
  • Guaifenesin (Guaiphenesin/Gyceral Guaiacolate) 100 mg
  • Guaiphenesin 100mg
  • Guaiphenesin IP 12.5 mg
  • Guaiphenesin 12.5 mg
  • Guaiphenesin 2 mg
  • Guaiphenesin 2.5 mg
  • Guaifenesin (Guaiphenesin/Gyceral Guaiacolate) 200 mg
  • Guaiphenesin 200 mg
  • Guaifenesin (Guaiphenesin/Gyceral Guaiacolate) 25 mg
  • Guaiphenesin 25 mg
  • Guaiphenesin 30 mg
  • Guaiphenesin 4 mg
  • Guaiphenesin 5 mg
  • Guaiphenesin 50 mg
  • Guaiphenesin IP 50 mg
  • Guaifenesin (Guaiphenesin/Gyceral Guaiacolate) 50 mg
  • Guaiphenesin 50.0 mg
  • Guaiphenesin 60 mg
  • Guaiphenesin 600 mg
  • Guaiphenesin 66.5 mg
  • Guaiphenesin 66.6 mg
  • Guaiphenesin 66.65 mg
  • Guaiphenesin IP 66.65 mg
  • Guaiphenesin 8 mg
  • Guaiphenesin 80 mg

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