Indications |
Oral Prophylaxis of migraine, Prophylaxis of vertigo and vestibular disorders, Prophylaxis of peripheral and cerebrovascular disorders Adult: 5-10 mg daily at bedtime. |
Contraindications |
Pregnancy, lactation, GI or urinary tract obstruction, acute porphyrias. |
Warnings / Precautions |
Driving or operating machinery, epilepsy, elderly, CVS disease, glaucoma. |
Adverse Reactions |
Drowsiness. Rarely wt gain, headache, depression, gastric pain, dry mouth, insomnia, extrapyramidal reactions, galactorrhoea. |
Drug Interactions |
Plasma levels reduced by phenytoin, carbamazepine, valproic acid. See Below for More flunarizine Drug Interactions |
Mechanism of Actions |
Flunarizine has H1-receptor blocking action and calcium-channel blocking effect. It has also been used as an adjunct epileptic therapy for patients refractory to standard treatment regimens. Absorption: Absorbed well from the GI tract (oral). Distribution: Highly lipophilic. Protein-binding: >90%. Metabolism: Extensive. Excretion: Via bile (as metabolites); 18 days (elimination half-life). |
Administration |
May be taken with or without food. |
Storage Conditions |
Oral: Store below 25°C. |
ATC Classification |
N07CA03 - flunarizine ; Belongs to the class of antivertigo preparations. |
Storage |
Oral: Store below 25°C. |
Available As |
|
Flunarizine
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Flunarizine Containing Brands
Flunarizine is used in following diseases
Drug - Drug Interactions of Flunarizine
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