Drotaverine

Indications	Oral Antispasmodic *Adult:* 40-80 mg tid. *Child:* 1-6 yr: 20 mg 3-4 times daiily; >6 yr: 40 mg tid.
Contraindications	Severe renal/hepatic/cardiac dysfunction. Porphyria.
Warnings / Precautions	Exercise caution in patients with renal/hepatic/cardiac dysfunction. Pregnacy, lactation.
Adverse Reactions	Vertigo, nausea, vomiting, dry mouth.
Drug Interactions	May attenuate the action of levodopa. Concurrent use of analgesics, antimuscarinics or benzodiazepines. Additive beneficial effect with concurrent use of analgesics, antimuscarinics or benzodiazepines. See Below for More drotaverine Drug Interactions
Mechanism of Actions	Drotaverine has antispasmodic effect mediated via inhibition of phosphodiesterase-IV, specific for smooth muscle. It has a rapid and direct action on the smooth muscle. It acts to correct cyclic AMP and Ca imbalance at the spastic site, thereby relieving smooth muscle spasm and pain.
Administration	May be taken with or without food.
ATC Classification	A03AD02 - drotaverine ; Belongs to the class of papaverine and derivatives. Used in the treatment of functional bowel disorders.
Available As	Drotaverine 10 mg Drotaverine 20 mg Drotaverine 40 mg Drotaverine 50 mg Drotaverine 60 mg Drotaverine 80 mg

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Drotaverine Containing Brands

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Drotaverine is used in following diseases

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Drug - Drug Interactions of Drotaverine

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