Indications |
Ophthalmic Ocular hypertension, Open-angle glaucoma Adult: As 2% eye drops: 1 drop tid; bid when used with a topical β-blocker. |
Contraindications |
Severe renal impairment; hypersensitivity; hyperchloraemic acidosis. Lactation. |
Warnings / Precautions |
Hepatic impairment; systemic absorption following topical admin; history of renal calculi or intraocular surgery; chronic corneal defects; risk of choroidal detachment when used after filtration procedures. |
Adverse Reactions |
Conjunctivitis; superficial punctate keratitis; ocular burning, stinging or itching; eyelid inflammation and crusting; blurred vision; lachrymation; anterior uveitis; transient myopia; corneal oedema; iridocyclitis; headache; dizziness; paraesthesia; asthenia; sinusitis; nausea; hypersensitivity reactions; bitter taste; epistaxis; urolithiasis; rhinitis. |
Drug Interactions |
Enhance effects of amphetamines, ephedrine, quinidine. Reduce effects of methenamine and its compounds. Enhance antiepileptic-induced osteomalacia. Severe acidosis and increased CNS toxicity with aspirin. Increased excretion of lithium. See Below for More dorzolamide Drug Interactions |
Mechanism of Actions |
Dorzolamide is a carbonic anhydrase inhibitor that reduces formation of hydrogen and carbonate ions from CO2 and water thereby reducing aqueous humor secretion, thus lowering intraocular pressure. |
Storage Conditions |
Ophthalmic: Store at 15-30°C. |
ATC Classification |
S01EC03 - dorzolamide ; Belongs to the class of carbonic anhydrase inhibitors. Used in the treatment of glaucoma. |
Storage |
Ophthalmic: Store at 15-30°C. |
Available As |
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Dorzolamide
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Dorzolamide Containing Brands
Dorzolamide is used in following diseases
Drug - Drug Interactions of Dorzolamide
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