Clobetasol

Indications
 Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: As propionate: Apply 0.05% cream/ointment onto affected area twice daily.
Elderly: Initiate with lower dose.
Renal impairment: Initiate with lower dose.
Hepatic impairment: Initiate with lower dose.
Contraindications
 Childn <12 yrs. Long-term treatment of ulcerative conditions, rosacea, pruritus; presence of acute infections. Hypersensitivity.
Warnings / Precautions
 Heart failure, recent myocardial infarction, hypertension; diabetes mellitus; epilepsy; glaucoma; hypothyroidism; hepatic failure, renal impairment; psychoses; childn and elderly. Should not enter eyes. If infection exists, treat with specific anti-infectives. Pregnancy, lactation.
Adverse Reactions
 Perioral dermatitis, striae esp in flexures. Dermal and epidermal atrophy esp on the face, steroid purpura.
Potentially Fatal: Prolonged usage of large amount of clobetasol propionate can lead to sufficient systemic levels to produce adrenal suppression, Cushing's syndrome, diabetes and hypertension.
Mechanism of Actions
 Clobetasol is a very potent corticosteroid used in short-term treatment of various inflammatory skin conditions.
Storage Conditions
 Topical/Cutaneous: Store below 25°C.
ATC Classification
 D07AD01 - clobetasol ; Belongs to the class of very potent (group IV) corticosteroids. Used in the treatment of dermatological diseases.
Storage
 Topical/Cutaneous: Store below 25°C.
Available As
  • Clobetasol 0.005% w/w
  • Clobetasol Propionate 0.025% w/w
  • Clobetasol 0.05%
  • Clobetasol Propionate 0.05%
  • Clobetasol 0.05% w/v
  • Clobetasol Propionate 0.05% w/v
  • Clobetasol Propionate 0.05% w/w
  • Clobetasol 0.05% w/w
  • Clobetasol Propionate 0.05%w/w
  • Clobetasol Propionate 0.055% w/w
  • Clobetasol Propionate 0.5%
  • Clobetasol 0.5%
  • Clobetasol Propionate 0.5% w/w
  • Clobetasol 0.5% w/w
  • Clobetasol Propionate 500 mcg
  • Clobetasol Propionate 75 mg

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