Calcium Chloride

Indications
Intravenous
Hypocalcaemia and calcium deficiency states
Adult: 10-25 mmol at intervals of 1-3 days, adjusted according to patient's needs and serum Ca readings. Ca chloride is given via slow iv at rate not exceeding 1 ml/min(10% solution).
Intravenous
Severe acute hypocalcaemia
Adult: 2.25 mmol by slow IV Inj repeated as required, or followed by 9 mmol/day as continuous IV infusion.
Intravenous
Hypocalcaemic tetany
Adult: 2.25 mmol by slow IV Inj repeated as required, or followed by 9 mmol/day as continuous IV infusion.
Intravenous
Severe hyperkalaemia
Adult: 5-10 ml of 10% solution, to be given over 2-5 min. May be repeated as necessary with ECG monitoring.
Child: 20 mg/kg, repeated every 10 min if needed.
Intravenous
Antidote in severe hypermagnesaemia
Adult: 5-10 ml of 10% solution, to be given over 2-5 min. May be repeated as necessary with ECG monitoring.
Child: 20 mg/kg, repeated every 10 min if needed.
Contraindications
Treatment of hypocalcaemia caused by renal insufficiency or in patients with resp acidosis or failure. Patients with Ca renal calculi or a history renal calculi; IM/SC administration. Parenteral therapy for patients receiving cardiac glycosides.
Warnings / Precautions
Impaired renal function; cardiac disease; hypercalcaemia-associated diseases, eg, sarcoidosis; other malignancies. Pregnancy.
Adverse Reactions
GI irritation: Soft-tissue calcification, skin sloughing or necrosis after IM/SC injection. Hypercalcaemia characterised by anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, nephrocalcinosis, renal calculi; chalky taste, hot flushes and peripheral vasodilation.
Potentially Fatal: Cardiac arrhythmias and coma.
Drug Interactions
Co-administration of high Ca doses with thiazide diuretics may result in milk-alkali syndrome and hypercalcaemia. May potentiate digoxin toxicity. Decreases effects of calcium-channel blockers. Enhanced absorption with calcitriol (a vit D metabolite).
See Below for More calcium chloride Drug Interactions
Mechanism of Actions
Calcium chloride is used to prevent or treat negative calcium balance. It also regulates action potential excitation threshold to facilitate nerve and muscle performance.
Absorption: Soluble calcium is predominantly absorbed from the small intestine by active transport and passive diffusion. Small intestines by active transport and passive diffusion. There is increased absorption in calcium deficiency states and during childhood, pregnancy and lactation.
Distribution: Crosses the placenta and enters breast milk.
Excretion: Excreted mainly in the kidneys (as excess calcium), faeces (as unabsorbed calcium) with traces found in sweat, skin, hair and nails.
Storage Conditions
Intravenous: Store at 15-30°C.
ATC Classification
G04BA03 - calcium chloride ; Belongs to the class of acidifiers. Used in the treatment of urological problems.
A12AA07 - calcium chloride ; Belongs to the class of calcium-containing preparations. Used as dietary supplements.
B05XA07 - calcium chloride ; Belongs to the class of electrolyte solutions used in I.V. solutions.
Storage
Intravenous: Store at 15-30°C.
Available As
  • Calcium Chloride 0.0146% w/v
  • Calcium Chloride 0.0146% w/w
  • Calcium Chloride 0.022 gm
  • Calcium Chloride 0.027 gm
  • Calcium Chloride 0.027%
  • Calcium Chloride 0.048%
  • Calcium Chloride 0.048% w/v
  • Calcium Chloride 0.048% w/w
  • Calcium Chloride 0.048%w/v
  • Calcium Chloride 0.052 gm
  • Calcium Chloride 0.055 gm
  • Calcium Chloride 0.15 mg
  • Calcium Chloride 0.22 gm
  • Calcium Chloride 1%
  • Calcium Chloride 1% w/v
  • Calcium Chloride 1.325% w/v
  • Calcium Chloride 1.35% w/v
  • Calcium Chloride 10% w/v
  • Calcium Chloride 12.5 meq
  • Calcium Chloride 3.45 mg
  • Calcium Chloride 3.85 mg
  • Calcium Chloride 40 mg
  • Calcium Chloride 52 mg
  • Subscribe for latest updates

    Subscribe to our e-mail newsletter to receive updates.

    No comments yet.

    Post Review about Calcium Chloride


    Calcium Chloride Containing Brands

    We are Developing Our database, More results coming soon.

    Calcium Chloride is used in following diseases

    We are Developing Our database, More results coming soon.

    Drug - Drug Interactions of Calcium Chloride

    We are Developing Our database, More results coming soon.